Hepatitis c virus conjugates

Details Hepatitis c virus conjugates Hepatitis c virus conjugates

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01) A61B 5/055 (2006.01) A61K 39/29 (2006.01) A61K 47/48 (2006.01) C07K 16/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2409287

The present invention features HCV conjugates able to induce an immune response recognizing different strains and variants of HCV. The conjugates contain a polypeptide or protein complex carrier and one or more HCV mimotopes. Preferred HCV mimotopes provide antigens able to generate antibodies recognizing the hypervariable region of the HCV E2 protein.

La présente invention concerne des conjugués du VHC, capables d'induire une réponse immunitaire reconnaissant différentes souches et variantes du VHC. Les conjugués contiennent un support de complexe polypeptidique ou protéique et un ou plusieurs mimotopes VHC. Les mimotopes VHC préférés sont à l'origine d'antigènes capables de produire des anticorps reconnaissant des domaines hypervariables de la protéine VHC E2.

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