A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/29 (2006.01) C07K 14/18 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2187299
Peptides representing portions of the Hepatitis C Virus core protein that represent cytotoxic T lymphoryte epitopes are disclosed. The peptides also have amino acid sequences corresponding to binding motifs for human HLA molecules. The peptides are useful as vaccines for the prevention or treatment of Hepatitis C Virus infection and can also be used as reagents for diagnostic tests for Hepatitis C Virus exposure or for prognostic tests for predicting the clinical course of Hepatitis C Virus infection.
Peptides représentant certaines parties de la protéine de noyau du virus de l'hépatite C, lesquelles parties représentent des épitopes de lymphocytes T cytotoxiques. Les peptides possèdent également des séquences d'acides aminés correspondant à des motifs de liaison pour les molécules de HLA humain. Les peptides sont utilisables en tant que vaccins destinés à la prophylaxie ou au traitement de l'infection par le virus de l'hépatite C, et peuvent également servir de réactifs dans les tests de diagnostic de l'exposition au virus de l'hépatite C, ou dans les tests de pronostic de l'évolution clinique d'une infection par le virus de l'hépatite C.
Berzofsky Jay A.
Feinstone Stephen
Shirai Mutsunori
Department Of Health And Human Services (the) National Institute
National Institute Of Health The Government Of The United States Of America Represented By Th
Swabey Ogilvy Renault
LandOfFree
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