Hepatitis e virus vaccine and method

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/29 (2006.01) A61K 39/385 (2006.01) A61K 39/42 (2006.01) C07K 14/08 (2006.01) C07K 16/10 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2125701

2125701 9314208 PCTABS00024 Antigen and antibody vaccine compositions effective in preventing hepatitis E virus (HEV) infection are disclosed. The antigen composition includes a peptide corresponding to a carboxyl terminal end region of the capsid protein encoded by the second open reading frame (2) of the HEV genome. The composition is effective in preventing HEV infection after vaccination. The antibody composition contains an antibody effective to block HEV infection of human primary hepatocytes in culture.

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