Hepatitis surface antigen particle vaccine

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/36 (2006.01) A61K 39/29 (2006.01) A61K 39/42 (2006.01) C07K 14/02 (2006.01) C07K 17/06 (2006.01) C12N 15/81 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1341021

Vaccines are provided produced by hybrid DNA technology for Hepatitis B virus comprising Hepatitis B 5 surface antigen particles containing a human polyalbumin binding site receptor. Constructs are provided for expression of the vaccine protein, which upon transformation, in an appropriate host results in the production of particles useful as vaccines. The yeast strain S. carlsbergensis strain 2150-2-3 (pHBpreS-347/33T) was deposited at the A.T.C.C. on 14 June 1984 and given Accession No. 20716.

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