Hepatocyte growth factor intron fusion proteins

Details Hepatocyte growth factor intron fusion proteins Hepatocyte growth factor intron fusion proteins

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 38/18 (2006.01) A61K 48/00 (2006.01) C07K 14/475 (2006.01) C07K 14/705 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 9/16 (2006.01)

Patent

CA 2628928

Isoforms of ligands, including isoforms of hepatocyte growth factor (HGF) containing an intron-encoded portion, and pharmaceutical compositions containing HGF isoforms are provided. The HGF ligand isoforms and compositions containing them can be used in methods of treatment of diseases, such as cancer and other angiogenic diseases

La présente invention se rapporte à des isoformes de ligands, notamment à des isoformes du facteur de croissance des hépatocytes (HGF) contenant une partie codée par un intron, et à des compositions pharmaceutiques contenant lesdites isoformes HGF. Les isoformes des ligands HGF et les compositions qui les contiennent peuvent être utilisées dans des méthodes de traitement de maladies telles que le cancer et d'autres maladies angiogéniques.

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