Hepatocyte growth factor variants

Details Hepatocyte growth factor variants Hepatocyte growth factor variants

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61K 38/48 (2006.01) A61K 47/48 (2006.01) C07K 14/475 (2006.01) C12N 9/64 (2006.01) C12N 15/57 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2118012

2118012 9323541 PCTABS00028 The invention concerns hepatocyte growth factor (HGF) amino acid sequence variants. The preferred variants are resistant to proteolytic cleavage by enzymes capable of in vivo conversion of HGF into its two-chain form and/or contain a mutation within the protease domain of HGF.

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