Her-2 diagnostic methods

Details Her-2 diagnostic methods Her-2 diagnostic methods

G - Physics

01

N

G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2711843

In certain aspects, the present invention provides methods for determining whether a Her-2 positive cancer is likely to respond to treatment with a Her2-acting agent and/or whether a patient with a Her-2 positive cancer is likely to have a slow disease progression. In other aspects, the present invention is drawn to methods for determining whether a subject with a Her-2 positive cancer is unlikely to respond to treatment with at least one chemotherapeutic agent in addition to a Her2-acting agent and/or whether a patient with a Her-2 positive cancer is likely to have a fast disease progression.

L'invention concerne, dans un aspect, des procédés pour déterminer si un cancer positif au Her-2 est susceptible de répondre à un traitement avec un agent agissant sur le Her-2 et/ou si un patient atteint d'un cancer positif au Her-2 est susceptible d'avoir une progression de maladie lente. Dans d'autres aspects, la présente invention concerne des procédés pour déterminer si un sujet atteint d'un cancer positif au Her-2 est non susceptible de répondre à un traitement avec au moins un agent chimiothérapeutique en plus d'un agent agissant sur le Her-2 et/ou si un patient atteint d'un cancer positif au Her-2 est susceptible d'avoir une progression de maladie rapide.

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