Herbal pharmaceutical compositions for treating...

A - Human Necessities – 61 – K

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A61K 36/88 (2006.01) A61K 9/08 (2006.01) A61K 9/14 (2006.01) A61K 36/28 (2006.01) A61K 36/484 (2006.01) A61K 36/78 (2006.01) A61K 36/8888 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2431852

The present invention provides pharmaceutical compositions which contain Ophiopogon (TuberOphiopogonis), pinellia (Tuber Pinelliae), raw licorice (Radix Glycyrrhizae), and one of the following herbs: lantern tridax (Herba Tridacis procumbentis), Taiwan adenostema (Herba Adenostematis), or heartleaf houttuynia (Herba houttuyniae). Optionally, a fifth herb, which is either tang- shen (Radix Codonopsitis) or American ginseng (Radix Pancis Quinquefolii), can be added. These pharmaceutical compositons are effective in treating patients with immunological disorders, particularly IgE-mediated diseases, such as asthma, atopic eczema, atopic dematitis, allergic rhinitis and rheumatoid arthritis. The present invention also provides methods for making the pharmaceutical compositions.

La présente invention concerne des compositions pharmaceutiques qui contiennent de l'ophiopogon (<i>Tuber </i><i>Ophiopogonis</i>), de la pinellia (<i>Tuber Pinelliae</i>), de la réglisse brute (<i>Radix Glycyrrhizae</i>) et une des herbes suivantes: lantern tridax (<i>Herba Tridacis procumbentis</i>), Taiwan adenostema (<i>Herba Adenostematis</i>), ou houttuynia cordata (<i>Herba houttuyniae</i>). Eventuellement une cinquième herbe, qui est soit le tang-shen (<i>Radix Codonopsitis</i>) soit le ginseng d'Amérique (<i>Radix Pancis Quinquefolii</i>), peut être ajoutée. Ces compositions pharmaceutiques sont efficaces pour traiter des patients atteints de troubles immunologiques, notamment les maladies induites par l'immunoglobuline E (IgE), telles que l'asthme, l'eczéma atopique, la dermatite atopique, la rhinite allergique et la polyarthrite rhumatoïde. Cette invention concerne également des méthodes de préparation desdites compositions pharmaceutiques.

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