Herpes simplex type 1 protease mutants and vectors

Details Herpes simplex type 1 protease mutants and vectors Herpes simplex type 1 protease mutants and vectors

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) C12N 9/50 (2006.01) C12N 15/57 (2006.01) C12N 15/86 (2006.01) C12N 15/869 (2006.01)

Patent

CA 2222877

Herpes Simplex Type 1 viruses having mutated protease genes are described, also are methods for introducing a point mutation in the protease gene, vectors used in this process, and host cells transformed with these vectors.

L'invention porte sur des virus de l'herpès simplex du type 1 présentant des gènes de protéase mutés; sur des méthodes d'introduction d'une mutation ponctuelle dans un gène de protéase; sur des vecteurs utilisés dans ces méthodes et sur des cellules hôtes transformées à l'aide de ces vecteurs.

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