Herpes simplex virus vp22 vaccines and methods of use

Details Herpes simplex virus vp22 vaccines and methods of use Herpes simplex virus vp22 vaccines and methods of use

A - Human Necessities

61

K

A61K 39/245 (2006.01) C07K 14/035 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2291010

Vaccines containing herpes simplex virus (HSV) VP22 polypeptides capable of eliciting a cellular immune reponse and methods for treating and preventing HSV infections using the vaccines are disclosed. The vaccines can include additional HSV polypeptides, such as HSV glycoproteins. Also disclosed are methods of DNA immunization.

Cette invention concerne des vaccins qui contiennent des polypeptides VP22 du virus de l'herpès simplex (VHS) permettant d'éliciter une réponse immune cellulaire. Cette invention concerne également des procédés de traitement et de prévention d'infections par le VHS qui font appel à ces vaccins. Ces vaccins peuvent également comprendre des polypeptides complémentaires de VHS, tels que des glycoprotéines de VHS. Cette invention concerne enfin des procédés d'immunisation au niveau de l'ADN.

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