Herpes virus vectors for dendritic cells

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 7/01 (2006.01) A61K 35/76 (2006.01) A61K 39/00 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 15/86 (2006.01) C12N 15/869 (2006.01)

Patent

CA 2337494

An attenuated herpes virus capable of efficiently infecting a dendritic cell without preventing antigen processing occurring within the infected cell. The attenuated herpes virus and dentrictic cells infected with the virus are useful in immunotherapeutic methods of treating disease.

L'invention concerne un virus d'herpès atténué capable d'infecter efficacement une cellule dendritique sans empêcher le traitement d'antigène de se produire dans la cellule infectée. Le virus d'herpès atténué et les cellules dendritiques infectées par ce virus peuvent servir dans des procédés immunothérapeutiques de traitement de maladies.

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