Herpes viruses for immune modulation

Details Herpes viruses for immune modulation Herpes viruses for immune modulation

C - Chemistry, Metallurgy

12

N

C12N 15/869 (2006.01) A61K 35/76 (2006.01) A61K 48/00 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2405458

Use of an attenuated herpes virus which lacks a functional vhs gene, or a functional equivalent thereof, in the manufacture of a medicament for use in a method of immunotherapy or vaccination comprising the infection of dentritic cells with said virus.

L'invention concerne l'utilisation du virus de l'herpès atténué dépourvu du gène vhs (protéine d'arrêt hôte du virion) fonctionnel, ou d'un équivalent fonctionnel de celui-ci, dans la fabrication d'un médicament s'utilisant dans un procédé d'immunothérapie ou de vaccination, notamment contre l'infection des cellules dentritiques par ledit virus.

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