(hetarylphenoxy)-(phenylpiperazinyl)-propanols, their...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/04 (2006.01) C07D 231/12 (2006.01) C07D 239/42 (2006.01) C07D 261/08 (2006.01) C07D 295/092 (2006.01) C07D 403/12 (2006.01) C07D 521/00 (2006.01)

Patent

CA 1202305

Abstract of the Disclosure: Novel (hetarylphenoxy)- (phenylpiperazinyl)-propanols of the formula Image I where R1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, and the heterocyclic structure Het. is pyrimidinyl, triazol- 1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, pro- cesses for their preparation, and pharmaceutical formula- tions which contain these compounds and exhibit predomin- antly hypotensive, sedative, neuroleptic and broncholytic properties.

394094

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