C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/06 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 221/08 (2006.01) C07D 237/26 (2006.01) C07D 241/38 (2006.01) C07D 487/06 (2006.01)
Patent
CA 2183735
This invention is directed to hetero-annulated indazoles of formula (I) and namely to 2,5-disubstituted quinolino-, isoquinolino-, phthalazino-, and quinoxalino-annulated indazole-6(2H)-ones and related mono N-oxides. These compounds have been shown to have antitumor activity.
L'invention concerne des indazoles hétéro-annelés de Formule (I), à savoir des indaxole-6(2H)-ones quinolino-, isoquinolino-, phtalazino- et quinoxalino 2,5- disubstitués et leurs mono N-oxydes apparentés. On a démontré que ces composés présentent une activité antitumorale.
Krapcho A. Paul
Menta Ernesto
Oliva Ambrogio
Spinelli Silvano
Boehringer Mannheim Italia Spa
Long And Cameron
Novuspharma S.p.a.
University Of Vermont
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