(hetero) aryl substituted benzofurans as 5-ht ligands

Details (hetero) aryl substituted benzofurans as 5-ht ligands (hetero) aryl substituted benzofurans as 5-ht ligands

C - Chemistry, Metallurgy

07

D

C07D 491/04 (2006.01) A61K 31/435 (2006.01) A61P 25/00 (2006.01) C07D 221/00 (2006.01) C07D 307/00 (2006.01)

Patent

CA 2451606

The present invention provides coupounds of formula (I): wherein R1, R2, R3, R4, R5, R6, X, ---, m, and n have any of the values defined in the specification, as well as pharmaceutical compositions comprising the compounds or salts thereof. The invention also provides therapeutic methods as well as processes and intermediates useful for preparing compounds of formula (I). The compounds are useful as 5-HT ligands.

L'invention concerne des composés représentés par la formule (I), dans laquelle R¿1?, R¿2?, R¿3?, R¿4?, R¿5?, R¿6?, X, ---, m, et n ont n'importe quelle valeur définie par le descriptif, ainsi que des compositions pharmaceutiques contenant lesdits composés ou des sels de ceux-ci. Par ailleurs, l'invention concerne des méthodes thérapeutiques, des procédés et des intermédiaires utilisés pour préparer les composés de formule (I). Ces composés sont utilisés comme ligands 5-HT.

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