Hetero isonipecotic modulators of vanilloid vr1 receptor

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/62 (2006.01) A61K 31/445 (2006.01) A61K 31/451 (2006.01) A61K 31/4523 (2006.01) A61P 29/00 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 417/06 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2572075

This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to hetero isonipecotic amides that are potent modulators of VR1 which are useful for the treatment and prevention of disease conditions in mammals.

L'invention concerne des ligands de récepteur vanilloïde VR1, et plus précisément des amides hétéro isonipécotiques qui sont de puissants modulateurs du VR1, utiles pour le traitement et la prévention de maladies chez les mammifères.

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