Heteroaromatic bicyclic derivatives useful as anticancer agents

Details Heteroaromatic bicyclic derivatives useful as anticancer agents Heteroaromatic bicyclic derivatives useful as anticancer agents

C - Chemistry, Metallurgy

07

D

C07D 403/10 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61K 31/5377 (2006.01) A61K 31/541 (2006.01) A61K 31/55 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01) C07D 239/94 (2006.01) C07D 401/10 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 417/14 (2006.01) C07D 451/02 (2006.01) C07D 453/02 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 491/048 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2290918

The invention relates to compounds of the formula 1 Image and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R1, R3 and R4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.

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