C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/14 (2006.01) A61K 31/14 (2006.01) A61P 25/18 (2006.01) C07D 413/14 (2006.01)
Patent
CA 2592986
The invention pertains to heteroaromatic compounds that serve as effective phosphodiesterase (PDE) inhibitors. In particular, the invention relates to said compounds which are selective inhibitors of PDE10. The invention also relates to intermediates for preparation of said compounds; pharmaceutical compositions comprising said compounds; and the use of said compounds in a method for treating certain central nervous system (CNS) or other disorders.
L'invention concerne des composés hétéroaromatiques qui sont utilisés comme inhibiteurs efficaces de la phosphodiesterase (PDE). D'une manière plus spécifique, l'invention concerne des composés hétéroaromatiques qui sont des inhibiteurs sélectifs de la PDE10. L'invention concerne également des intermédiaires pour la préparation de ces composés ; des compositions pharmaceutiques contenant ces composés ; et l'utilisation de ces composés dans une méthode permettant de traiter certains troubles du système nerveux central ou autres.
Helal Christopher John
Hoover Dennis Jay
Humphrey John Michael
Verhoest Patrick Robert
Pfizer Products Inc.
Torys Llp
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