Heteroaryl antagonists of prostaglandin d2 receptors

Details Heteroaryl antagonists of prostaglandin d2 receptors Heteroaryl antagonists of prostaglandin d2 receptors

C - Chemistry, Metallurgy

07

D

C07D 211/80 (2006.01) A61K 31/4418 (2006.01) A61P 9/02 (2006.01) A61P 11/00 (2006.01) C07D 213/02 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2737739

Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.

Les composés ci-décrits sont des composés qui sont des antagonistes des récepteurs PGD2. Des compositions pharmaceutiques sont également décrites, qui comprennent les composés ci-décrits, ainsi que des procédés d'utilisation de ces antagonistes des récepteurs PGD2, seuls ou en combinaison avec d'autres composés, pour traiter les affections ou les maladies respiratoires, cardiovasculaires, et autres affections ou maladies dépendantes ou médiées par les PGD2.

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