Heteroaryl cinnamic acids as inhibitors of leukotriene...

Details Heteroaryl cinnamic acids as inhibitors of leukotriene... Heteroaryl cinnamic acids as inhibitors of leukotriene...

C - Chemistry, Metallurgy

07

D

C07D 493/08 (2006.01) A61K 31/19 (2006.01) A61K 31/33 (2006.01) C07C 59/68 (2006.01) C07D 307/54 (2006.01) C07D 309/06 (2006.01) C07D 309/10 (2006.01) C07D 333/24 (2006.01) C07D 335/02 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/00 (2006.01) C07D 409/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2125830

-89- Compounds having the formula I: (see formula I) are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

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