C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4985 (2006.01) A61P 35/00 (2006.01) C07D 487/04 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2666618
Provided herein are Heteroaryl Compounds having the following structure: (I) wherein R1, R2, L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof.
L'invention concerne des composés hétéroaryle de formule (I). Dans cette formule, R1, R2, L, X, Y, Z, Q, A et B sont définis dans la description. L'invention concerne également des compositions comprenant une quantité efficace d'un composé hétéroaryle, et des procédés de traitement ou de prévention d'un cancer, de troubles inflammatoires, de troubles immunologiques, de troubles métaboliques et de troubles pouvant être traités ou prévenus par inhibition d'une voie kinase. Ces procédés consistent à administrer une quantité efficace d'un composé hétéroaryle à un patient qui en a besoin.
Albers Ronald J.
Delgado Mederos Maria Mercedes
Harris Roy Leonard III
Huang Dehua
Lee Branden G.
Osler Hoskin & Harcourt Llp
Signal Pharmaceuticals Llc
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