C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/82 (2006.01) A61K 31/505 (2006.01) A61P 35/00 (2006.01) C07D 239/48 (2006.01) C07D 251/18 (2006.01) C07D 403/04 (2006.01) C07D 403/08 (2006.01) C07D 473/32 (2006.01) C07D 498/04 (2006.01)
Patent
CA 2659894
This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.
L'invention concerne des composés qui inhibent les enzymes d'activation E1, des compositions pharmaceutiques comprenant les composés, et des procédés d'utilisation des composés. Les composés sont utiles pour le traitement de troubles, en particulier de troubles de la prolifération cellulaire, y compris des cancers, des troubles inflammatoires et neurodégénératifs ; et une inflammation associée à une infection et une cachexie cancéreuse.
Claiborne Christopher F.
Critchley Stephen
Cullis Courtney
Langston Steven P.
Mizutani Hirotake
Millennium Pharmaceuticals Inc.
Robic
LandOfFree
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