Heteroaryl-fused pyrazolo derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 487/04 (2006.01) A61K 31/4162 (2006.01) A61K 31/4985 (2006.01) A61K 31/519 (2006.01) A61P 19/02 (2006.01) A61P 25/28 (2006.01) C07D 231/00 (2006.01) C07D 239/00 (2006.01) C07D 241/00 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2558109

Compounds of formula (I): where A, B, X, Y, Z, k, R1, R2 and R3 are those defined herein, and compositions comprising the same. The present invention also provides methods for preparing compounds of formula (I) and using the same in treating p38 mediated disorders in a patient.

L'invention concerne des composés représentés par la formule (I), dans laquelle A, B, X, Y, Z, k, R?1¿, R?2¿ et R?3¿ sont tels que définis dans le descriptif, et des compositions comprenant ceux-ci. Elle concerne aussi des procédés d'élaboration des composés représentés par la formule (I), et des procédés d'utilisation de ceux-ci pour traiter, chez un patient, des troubles induits par p38.

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