C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/44 (2006.01) A61K 31/498 (2006.01) A61P 37/02 (2006.01) C07D 215/60 (2006.01) C07F 9/6509 (2006.01)
Patent
CA 2503770
The present invention relates to compounds of the formula (I) wherein R1, R2, R3, R4, R5, R7, and L are as described in the specification. The present invention also relates to pharmaceutical compositions that include compounds of the formula (I) and a pharmaceutically acceptable carrier. Moreover, the present invention relates to methods of using the above-described compounds and compositions to treat and prevent diseases and conditions including those that may be treated or prevented by antagonizing the CCR1 receptor.
La présente invention concerne des composés représentés par la formule (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, R?7¿ et L sont tels que décrits dans le descriptif; des compositions pharmaceutiques qui comprennent des composés de formule (I) et un support pharmaceutiquement acceptable. De plus, cette invention concerne des méthodes d'utilisation desdits composés et desdites compositions pour traiter et prévenir des maladies et des pathologies y compris celles qui peuvent être traitées ou prévenues par une action antagoniste dirigée contre le récepteur CCR1. Formule (I)
Brown Matthew Frank
Gaweco Anderson See
Gladue Ronald Paul
Kath John Charles
Poss Christopher Stanley
Pfizer Products Inc.
Smart & Biggar
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