Heteroaryl peptidomimetics as thrombin receptor antagonists

Details Heteroaryl peptidomimetics as thrombin receptor antagonists Heteroaryl peptidomimetics as thrombin receptor antagonists

C - Chemistry, Metallurgy

07

K

C07K 5/06 (2006.01) C07K 5/072 (2006.01) C07K 5/08 (2006.01)

Patent

CA 2508891

The invention is directed to novel heteroaryl peptidomimetic compounds in particular indazole, indole or benzidazole amido peptidomimetic compounds, which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, angiogenesis and related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted heteroaryl peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.

L'invention concerne des composés hétéroaryles peptidomimétiques utiles en tant qu'antagonistes de récepteur de la thrombine dans le traitement de maladies associées à la thrombose, la resténose, l'hypertension, l'insuffisance cardiaque, l'arythmie, l'inflammation, l'angine, l'accident vasculaire cérébral, l'athérosclérose, les troubles ischémiques, l'angiogenèse, et les troubles associés, le cancer et les troubles neurodégénératifs. L'invention concerne également des compositions pharmaceutiques comprenant ces composés hétéroaryles peptidomimétiques substitués et des procédés de traitement des troubles induits par le récepteur de la thrombine.

Affiliated with

Also associated with

Rating

Heteroaryl peptidomimetics as thrombin receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Heteroaryl peptidomimetics as thrombin receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heteroaryl peptidomimetics as thrombin receptor antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2040834