Heteroaryl substituted pyridazinone derivatives

Details Heteroaryl substituted pyridazinone derivatives Heteroaryl substituted pyridazinone derivatives

C - Chemistry, Metallurgy

07

D

C07D 403/14 (2006.01) A61K 31/501 (2006.01) A61P 25/00 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2749867

The present invention is concerned with novel pyridazinone derivatives of formula (I) wherein R1, R2, R3 and R4 are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit PDE10A and can be used as medicaments.

L'invention concerne de nouveaux dérivés de pyridazinone représentés par la formule (I), dans laquelle R1, R2, R3 et R4 sont tels que définis dans le descriptif et les revendications, ainsi que des sels et des esters physiologiquement acceptables de ces composés. Lesdits composés inhibent la PDE10A et peuvent être utilisés comme médicaments.

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