C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/41 (2006.01) A61K 31/4439 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 405/14 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01)
Patent
CA 2462289
Tetrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl of formula (I): (see formula I) and pharmaceutically acceptable salts thereof are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, and panic, as well as in the treatment of pain and other diseases.
L'invention a trait à des composés de tétrazole substitués, directement ou au moyen d'un pont, par un groupe fonctionnel hétéroaryle contenant N à une position adjacente au point de liaison de l'hétéroaryle. Lesdits composés sont des modulateurs de mGluR5, utiles pour le traitement de troubles psychiatriques ou de l'humeur tels que, par exemple, la schizophrénie, l'anxiété, la dépression et la panique, ainsi que pour le traitement de la douleur et celui d'autres maladies.
Chen Chixu
Cosford Nicholas D.
Reger Thomas
Roppe Jeffrey
Smith Nicholas
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Heteroaryl substituted tetrazole modulators of metabotropic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Heteroaryl substituted tetrazole modulators of metabotropic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heteroaryl substituted tetrazole modulators of metabotropic... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1874047