Heteroaryl substituted thiazoles

Details Heteroaryl substituted thiazoles Heteroaryl substituted thiazoles

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) A61K 31/4436 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2687817

The invention provides heteroaryl substituted thiazolo compounds of Formula I and II and pharmaceutically acceptable salts thereof. The variables A and R3 to R7 are defined herein. The invention also includes methods for preparing compounds and salts of Formula I and II. The present invention also includes pharmaceutical compositions containing heteroaryl substituted thiazolo compounds and methods for using heteroaryl substituted thiazolo compounds, including methods for using the compounds in the treatment of hepatitis C virus.

La présente invention concerne des composés thiazoles à substitution hétéroaryle de formule I et II, ainsi que leurs sels dérivés pharmaceutiquement acceptables. Les variables A et R3 à R7sont définies ci-après. L'invention porte aussi sur des procédés de préparation des composés et des sels de formule I et II. En outre, la présente invention a trait à des compositions pharmaceutiques renfermant des composés de thiazole à substitution hétéroaryle, ainsi qu'à des procédés d'utilisation des composés de thiazole à substitution hétéroaryle, notamment des procédés d'utilisation de ces composés pour le traitement du virus de l'hépatite C.

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