C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/327 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 38/05 (2006.01) C07D 207/337 (2006.01) C07D 231/12 (2006.01) C07D 233/54 (2006.01) C07D 233/56 (2006.01) C07D 307/54 (2006.01) C07D 333/24 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/00 (2006.01) C07D 413/06 (2006.01) C07D 487/08 (2006.01) C07D 498/08 (2006.01) C07D 521/00 (2006.01) C07K 5/0
Patent
CA 2267879
The present invention is directed to compound of formula (I), wherein R1, R2, R3, R4, R5, X, Y and (Ia) are as defined herein. These compounds are useful for inhibiting the activity of a metalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds.
La présente invention porte sur un composé de la formule (I) dans laquelle R1, R2, R3, R4, R5, X, Y et (Ia) sont tels que définis dans la demande. Ces composés sont utiles pour inhiber l'activité d'une métalloprotéinase en mettant en contact cette métalloprotéinase avec une quantité efficace des composés de l'invention.
Abreo Melwyn A.
Bender Steven L.
Billedeau Roland J.
Castelhano Arlindo L.
Chen Jian Jeffrey
Agouron Pharmaceuticals Inc.
Sim & Mcburney
Syntex (u.s.a.) Inc.
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