Heteroaryl-ureas and their use as glucokinase activators

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 277/48 (2006.01) C07D 213/75 (2006.01) C07D 233/88 (2006.01) C07D 241/20 (2006.01) C07D 261/14 (2006.01) C07D 271/08 (2006.01) C07D 277/56 (2006.01) C07D 277/60 (2006.01) C07D 277/82 (2006.01) C07D 285/08 (2006.01) C07D 285/12 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2551324

This invention relates to compounds that are of formula (I) wherein A is heteroaryl and R1 and R2 are both cyclic residues, that are activators of glucokinase and thus may be useful for the management, treatment, control, or adjunct treatment of diseases, where increasing glucokinase activity is beneficial .

L'invention concerne des composés qui correspondent à la formule (I) dans laquelle A est un hétéroaryle et R?1¿ et R?2¿ sont tous deux des résidus cycliques, qui sont des activateurs de glucokinase et peuvent, de ce fait, s'utiliser pour gérer, traiter ou pour lutter contre des maladies ainsi qu'en tant que traitement auxiliaire lorsque l'augmentation des activités de glucokinase a un effet bénéfique.

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