Heteroarylamino and heteroarylsulfonamido substituted...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/12 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) C07D 263/16 (2006.01) C07D 277/32 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/14 (2006.01) C07D 453/02 (2006.01) C07D 471/08 (2006.01) C07D 471/18 (2006.01)

Patent

CA 2171972

The present invention relates to novel heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethylpiperidines and, specifically, to compounds of formula ()7, wherein W, Rt, R3, P and A are as defined in the specification, and to intermediates used in the synthesis of such compounds. The novel compounds of formula (n are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders.

La présente invention se rapporte à de nouveaux 3-benzylaminométhyl-pipéridines à substitution hétéroarylamino et hétéroarylsulfonamido, et, plus particulièrement, à des composés de la formule (I), dans laquelle W, R<1>, R<3>, P et A sont tels que définis dans le descriptif, ainsi qu'à des intermédiaires utilisés pour la synthèse de ces composés. Les nouveaux composés de la formule (I) conviennent au traitement de troubles inflammatoires et du système nerveux central, ainsi que d'autres troubles.

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