Heteroarylpiperidines, pyrrolidines and piperazines and...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/04 (2006.01) A61K 31/395 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C07D 231/56 (2006.01) C07D 275/06 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/00 (2006.01) C07D 403/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2175212

Heteroaryl compounds of structure Image where X is -O-, -S-, -NH-, or -NR2- and Q1 is a substituted piperidine, pyrrolidine, or piperazine are useful as antipsychotic and analgesic agents. The compounds are especially useful for treating psychoses by administering to a mammal a psychoses- treating effective amount of one of the compounds. Depot derivatives of the compounds are useful for providing long acting effects of the compounds. The compounds are also useful as analgesics by administering a pain-relieving effective amount of one of the compounds to a mammal.

Hétéroarylpipéridines, pyrrolidines et pipérazines utilisés comme antipsychotiques et analgésiques. Ces composés s'avèrent particulièrement utiles dans le traitement des psychoses des mammifères, qui s'opère par administration de doses à effet traitant de l'un d'eux. Leurs dérivés par déposition leur confèrent une efficacité de longue durée. Ils s'avèrent également efficaces comme analgésiques lorsque l'un d'eux est administré en doses à effet traitant.

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