Heteroaryls amide derivatives and their use as glucokinase...

Details Heteroaryls amide derivatives and their use as glucokinase... Heteroaryls amide derivatives and their use as glucokinase...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/455 (2006.01) A61P 3/10 (2006.01) C07D 403/12 (2006.01) C07D 405/14 (2006.01) C07D 513/04 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 2735184

The present invention provides Formula (1A) compounds that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase. X, Y, Z, R1, R2, R3, and R4 are as described herein.

La présente invention porte sur des composés de Formule (1A) qui servent d'activateurs de la glucokinase; sur des compositions pharmaceutiques de ceux-ci; et sur des procédés de traitement de maladies, de troubles, ou d'affections à médiation par la glucokinase. X, Y, Z, R1, R2, R3 et R4 sont tels que spécifiés dans la description.

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