C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01) A61K 31/4184 (2006.01) A61K 31/423 (2006.01) A61K 31/428 (2006.01) A61K 31/4745 (2006.01) A61K 31/517 (2006.01) A61P 7/02 (2006.01) C07D 221/00 (2006.01) C07D 263/00 (2006.01) C07D 277/00 (2006.01) C07D 333/00 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2408156
The invention relates to novel compounds of formula (I) containing benzofused heterocyclic sulfonamide derivatives which are effective platelet ADP receptor inhibitors. Such compounds including pharmaceutically acceptable salts are useful in various pharmaceutical compositions for the prevention and/or treatment of cardiovascular disease particularly those related to thrombosis.
La présente invention concerne de nouveaux composés représentés par la formule (I), contenant des dérivés de sulfonamides hétérobicycliques benzocondensés qui sont des inhibiteurs de récepteur ADP des plaquettes efficaces. Ces composés comprenant des sels pharmaceutiquement acceptables conviennent dans diverses compositions pharmaceutiques destinées à la prévention et au traitement de maladies cardio-vasculaires et en particulier de celles qui sont liées aux thromboses.
Marlowe Charles K.
Scarborough Robert M.
Fetherstonhaugh & Co.
Millennium Pharmaceuticals Inc.
Portola Pharmaceuticals Inc.
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