C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/417 (2006.01) A61K 31/4178 (2006.01) A61K 31/435 (2006.01) C07D 233/64 (2006.01) C07D 401/14 (2006.01)
Patent
CA 2590811
The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts or tautomers thereof, which are inhibitors of histone deacetylase (HDAC). The compounds of the present invention are useful for treating cellular proliferative diseases, including cancer. Further, the compounds of the present invention are useful for treating neurodegenerative diseases, schizophrenia and stroke among other diseases.
La présente invention concerne des composés représentés par la formule (I) ou des sels pharmaceutiquement acceptables ou des tautomères de ceux-ci, lesquels composés sont des inhibiteurs d'histone désacétylase (HDAC). Les composés de la présente invention servent au traitement de maladies prolifératives cellulaires, telles que le cancer. Les composés de la présente invention servent également à traiter diverses autres maladies telles que des maladies neurodégénératives, la schizophrénie et l'accident vasculaire cérébral.
Attenni Barbara
Bufi Laura Llauger
Ferrigno Federica
Ingenito Raffaele
Jones Philip
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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