C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) A61K 31/4427 (2006.01) A61K 31/4709 (2006.01) A61K 31/497 (2006.01) A61K 31/5025 (2006.01) A61K 31/517 (2006.01) A61K 31/519 (2006.01) A61P 25/00 (2006.01) C07D 213/65 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2701594
The present invention is directed to heterocycle phenyl amide compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T- type calcium channels are involved.
Cette invention concerne des composés de phényle amide hétérocyclique qui sont des antagonistes des canaux calciques de type T et qui sont utiles pour traiter ou prévenir des troubles et des maladies dans lesquels sont impliqués les canaux calciques de type T. Cette invention concerne également des compositions pharmaceutiques comprenant ces composés ainsi que l'utilisation de ces composés et de ces compositions pour prévenir ou traiter des maladies dans lesquelles sont impliqués les canaux calciques de type T.
Barrow James C.
Coleman Paul J.
Reger Thomas S.
Schlegel Kelly-Ann S.
Shu Youheng
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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