Heterocycle-substituted benzenemethanamine derivatives

Details Heterocycle-substituted benzenemethanamine derivatives Heterocycle-substituted benzenemethanamine derivatives

C - Chemistry, Metallurgy

07

D

C07D 213/74 (2006.01) A61K 31/33 (2006.01) C07D 213/85 (2006.01) C07D 213/89 (2006.01) C07D 215/42 (2006.01) C07D 215/46 (2006.01) C07D 221/04 (2006.01) C07D 231/38 (2006.01) C07D 239/42 (2006.01) C07D 241/20 (2006.01) C07D 333/44 (2006.01)

Patent

CA 2125675

2125675 9313069 PCTABS00024 The present invention is concerned with antiretroviral (e.g. anti-HIV-1) compounds having formula (I), wherein R1 and R2 each independently are halo or methyl; R3 is hydrogen, halo, nitro or trifluoromethyl; R4 is trifuloromethyl or methylcarbonyl; or a radical -C(=X)-NR5R6 wherein X is 0 or S, and R5 and R6 each independently are hydrogen or C1-4alkyl; or a radical -Alk-R7, wherein Alk is C1-4alkanediyl; and R7 is hydrogen or hydroxy; Het is a heterocycle radical of formulae (a); (b); (c); (d) or (e). Pharmaceutical compositions containing said compounds of formula (I) and processes of preparing said compounds and compositions.

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