Heterocycles

Details Heterocycles Heterocycles

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07D 211/96 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/04 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2285120

The present invention provides a compound of the formula:- Image or a pharmaceutically acceptable acid addition salt thereof, wherein Ar is phenyl substituted by 1 or 2 substituent(s) each independently selected from fluoro and chloro; X is NSO2(C1-C4 alkyl), NSO2(halo(C1-C4 alkyl)) or O; m is 0 or 1; n is 1 or 2; p is 1 or 2; q is 1 or 2; and r is 1 or 2, together with processes for the preparation of, intermediates used in the preparation of, compositions containing and uses of, such derivatives. The compounds have tachykinin receptor antagonist activity.

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