Heterocycles as nicotinic acid receptor agonists for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 491/04 (2006.01) A61K 31/519 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2608405

A compound having the general structure of Formula (I): Formula (I) or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, wherein: Q is selected from the group consisting of: Formula (a), (b), (c), (d) and (e); and L is selected from the group consisting of: Formula (f), (g), (h), and (i); or a pharmaceutically acceptable salt, solvate, ester, or tautomer thereof, are useful in treating diseases, disorders, or conditions such as metabolic syndrome and dyslipidemia.

L'invention concerne un composé représenté par la formule générale (I), ou un sel, un solvate, un ester, ou un tautomère acceptable d'un point de vue pharmaceutique de celui-ci, formule dans laquelle Q est sélectionné dans le groupe formé de (a), (b), (c), (d) et (e); et L est sélectionné dans le groupe formé de (f), (g), (h), et (i); ou un sel, un solvate, un ester, ou un tautomère acceptable d'un point de vue pharmaceutique de celui-ci, utilisés dans le traitement de maladies, de troubles ou d'états pathologiques tels que le syndrome métabolique et la dyslipidémie.

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