Heterocycles as protein kinase inhibitors

Details Heterocycles as protein kinase inhibitors Heterocycles as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4192 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2724715

Selected fused imidazole or triazole derivatives are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions in-volving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermedi-ates useful in such processes.

L'invention concerne des dérivés d'imidazole ou de triazole fusionnés sélectionnés qui sont efficaces pour la prophylaxie et le traitement de maladies, telles que des maladies à médiation par HGF. L'invention englobe de nouveaux composés, analogues, promédicaments et leurs sels de qualité pharmaceutique, des compositions pharmaceutiques et des procédés pour la prophylaxie et le traitement de maladies et d'autres affections ou troubles impliquant le cancer et autres. L'invention concerne également des procédés de préparation de tels composés ainsi que des intermédiaires utiles dans de tels procédés.

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