C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/02 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) C07D 215/00 (2006.01) C07D 217/00 (2006.01)
Patent
CA 2574956
The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
La présente invention a trait à des composés qui sont potentialisateurs de récepteurs métabotropiques du glutamate, comprenant le récepteur mGluR2, et qui sont utiles dans le traitement ou la prévention de troubles neurologiques et psychiatriques associés au dysfonctionnement de glutamate et de maladies dans lesquelles des récepteurs métabotropiques du glutamate sont impliqués. L'invention a également trait à des compositions pharmaceutiques comportant ces composés et à l'utilisation de ces composés et compositions dans la prévention ou le traitement de telles maladies dans lesquelles des récepteurs métabotropiques du glutamate sont impliqués.
Bonnefous Celine
Cube Rowena V.
Govak Steven P.
Huang Dehua
Hutchinson John H.
Merck & Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
LandOfFree
Heterocyclic acetophenone potentiators of metabotropic... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Heterocyclic acetophenone potentiators of metabotropic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heterocyclic acetophenone potentiators of metabotropic... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1696754