Heterocyclic amide derivatives

Details Heterocyclic amide derivatives Heterocyclic amide derivatives

C - Chemistry, Metallurgy

07

D

167/208, 260/308

C07D 231/56 (2006.01) A61K 31/40 (2006.01) C07D 209/18 (2006.01) C07D 235/04 (2006.01) C07D 249/18 (2006.01) C07D 265/36 (2006.01) C07D 333/60 (2006.01) C07D 403/10 (2006.01)

Patent

CA 1340567

The invention concerns novel) pharmaceutically useful, amide derivatives of certain benzoheter- ocyclylalkanoic acids (and related tetrazoles and acylsulphonamides) of the formula I and salts thereof) wherein the radicals R1, R2, L, X, Y, Z, A1, Q, A2 and M have the meanings set out in the specification. The invention also includes pharmaceutical compositions incorporating a formula. I compound or a salt thereof, a process for the manufacture of the said compound, together with intermediates for use in the latter process. The compounds of the invention are particularly useful leukotriene antagonists, and in the treatment of allergic diseases, inflammatory diseases, eridotoxic conditions or traumatic shock conditions.

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