Heterocyclic amides with alpha-4 integrin antagonist activity

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/078 (2006.01) A61K 31/4025 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 35/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2477943

The present invention relates to new compounds of Formula (I) and the salts, solvates and prodrugs thereof, wherein the meanings for the various substituents are as disclosed in the description. These compounds are useful as integrin .alpha.4 antagonists.

La présente invention se rapporte à de nouveaux composés de formule I et à leurs sels, solvates et promédicaments, tels que définis dans le descriptif. Ces composés sont utilisés comme antagonistes de l'intégrine .alpha.¿4?.

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