Heterocyclic amino-alcohol derivatives and their preparation

Details Heterocyclic amino-alcohol derivatives and their preparation Heterocyclic amino-alcohol derivatives and their preparation

C - Chemistry, Metallurgy

07

D

260/319, 260/327

C07D 335/06 (2006.01) C07D 209/08 (2006.01) C07D 211/14 (2006.01) C07D 265/36 (2006.01) C07D 307/79 (2006.01) C07D 327/06 (2006.01) C07D 333/54 (2006.01) C07D 333/56 (2006.01) C07D 337/08 (2006.01) C07D 339/08 (2006.01)

Patent

CA 1094088

ABSTRACT OF THE DISCLOSURE Amino-alcohol derivative having the formula : Image (I) wherein : (a) R1 represents hydrogen, one or two linear or ramified alkyl radicals (C1-C3), a phenyl radical or a carboxy radical; (b) R2 is a linear or ramified alkyl radical (C1-C3); (c) R3 is : - a mono or polyunsaturated alkenyl radical (C3-C18); - a mono or polylunsaturated alkenyl radical (C3-C12) substituted by oxygen, sulfur or a phenyl radical; - a mono or polyunsaturated alkynyl radical (C3-C18); - a mono or polyunsaturated alkynyl radical (C3-C12) substituted by oxygen, sulfur or a phenyl radical; - a cycloalkyl radical (C3-C10); - a linear or ramified alkyl radical (C2-C10); - a linear or ramified alkyl radical (C2-C18), substituted by at least an atom and/or radical selected from the group comprising: (1) oxygen or sulfur , (2) alkoxycarbonyl radicals (C1-C3), pyrrolidine, pyrroli- dinone or imidazolidone, (3) phenyl, phenoxy, phenylthio, benzoyl, indanyloxy, naphthyloxy radicals, (4) phenyl, phenoxy, phenylthio, benzoyl radicals substitu- ted by one or more alkyl (C1-C4) or alkoxy (C1-C4) radi- cals, by one or two halogen atoms, by nitrile, hydroxy, amino, alkanoyl (C2-C6), acylamino (C2-C4), alkoxycarbonyl (C1-C4) or alkylsulfonamido (C1-C4) radical, (d) R4 is hydrogen or when taken with R3 and adjacent nitro- gen atom, they form a morpholine, pyrrolidine, piperidine radical or a piperidine radical substituted by one or two alkyl (C1-C4), phenyl or phenylalkyl (C1-C4) radicals, or a piperazine radical substituted in position 4 by a phenyl radical or by a phenyl radical itself substituted by (1) one or two alkyl (C1-C4) or alkoxy (C1-C4) radicals, (2) one or two halogen atoms, or (3) a trifluoromethyl radical; (e) R5 is hydrogen or an alkyl (C1-C3) radical; (f) R6 is hydrogen or a linear or ramified alkanoyl (C1-C10) radical or a cycloalkanoyl (C3-C8) radical; (g) n is equal to 1,2 or 3; (h) X is sulfur, oxygen, a CH2 radical or a NH radical; (i) Y is a CH2 radical or sulfur; (j) when simultaneously X is oxygen, Y is a CH2 group, n is equal to 2, R1 and R5 are hydrogen, R2 is methyl and R6 is hydrogen or an alkanoyl radical, R4 does not form a substituted piperazine radical with R3 and adjacent nitrogen atom.

266041

Affiliated with

Also associated with

Rating

Heterocyclic amino-alcohol derivatives and their preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Heterocyclic amino-alcohol derivatives and their preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Heterocyclic amino-alcohol derivatives and their preparation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-132711