Heterocyclic aminopyrrolidine derivatives as melatonergic...

Details Heterocyclic aminopyrrolidine derivatives as melatonergic... Heterocyclic aminopyrrolidine derivatives as melatonergic...

C - Chemistry, Metallurgy

07

D

C07D 405/10 (2006.01) A61K 31/4025 (2006.01)

Patent

CA 2376949

There is provided a novel series of heterocyclic aminopyrrolidine compounds of Formula (I) wherein R1, R2, R3, R4, W, Z and the wavy bond are as defined herein which bind to the human melatonin receptor and therefore are useful as melatonergic agents.

L'invention concerne une nouvelle série de composés d'aminopyrrolidine hétérocycliques de formule I, dans laquelle R<1>, R<2>, R<3>, R<4>, W, Z et la liaison ondulée sont tels que définis, composés se liant au récepteur de la mélatonine humaine et donc utiles en tant qu'agent mélatonergiques.

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