Heterocyclic antiviral arylpyridone derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 213/64 (2006.01) A61K 31/4412 (2006.01) C07D 401/10 (2006.01) C07D 417/10 (2006.01)

Patent

CA 2741325

Compounds having the formula (I) wherein R1, R2, R3a, R3b, R3c, R4, R5 and p are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.

La présente invention concerne des composés de formule (I) dans laquelle R1, R2, R3a, R3b, R3c, R4, R5 et p sont tels que définis ici, qui sont des inhibiteurs de la NS5b polymérase du virus de lhépatite C. Linvention concerne également des compositions et des procédés destinés à traiter une infection par le VHC et à inhiber la réplication du VHC.

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