Heterocyclic antiviral compounds

Details Heterocyclic antiviral compounds Heterocyclic antiviral compounds

C - Chemistry, Metallurgy

07

D

C07D 213/64 (2006.01) A61K 31/4412 (2006.01) A61K 31/4965 (2006.01) A61K 31/50 (2006.01) A61K 31/513 (2006.01) A61P 31/14 (2006.01) C07D 213/76 (2006.01) C07D 237/14 (2006.01) C07D 239/54 (2006.01) C07D 241/18 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2758838

Compounds having the formula I wherein R1, R2, R3, R4, R5a, R5b, R5c and R6 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.

L'invention concerne des composés de formule I dans laquelle R1, R2, R3, R4, R5a, R5b, R5c et R6 sont tels que définis dans le descriptif. Ces composés sont des inhibiteurs de la polymérase NS5b du virus de l'hépatite C. L'invention concerne également des compositions et des procédés de traitement d'une infection à VHC et d'inhibition de la réplication du VHC.

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