C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/84 (2006.01) A61K 31/343 (2006.01) A61P 31/14 (2006.01) C07D 407/04 (2006.01) C07D 407/12 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2714254
Compounds having the formula (I) wherein Y, R1, R4, A1, A2 and X2 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
L'invention porte sur des composés ayant la formule (I), dans laquelle Y, R1, R4, A1, A2 et X2 sont tels que définis dans la description, et qui sont des inhibiteurs de polymérase NS5b du virus de l'hépatite C. L'invention porte également sur des compositions et des procédés pour traiter une infection par le VHC et inhiber la réplication du VHC.
Labadie Sharada Shenvi
Lin Clara Jeou Jen
Talamas Francisco Xavier
Weikert Robert James
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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