Heterocyclic antiviral compounds

Details Heterocyclic antiviral compounds Heterocyclic antiviral compounds

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/5025 (2006.01) A61P 31/12 (2006.01) A61P 31/18 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2709348

Compounds of formula (I), wherein R1, R2, R3, X1, X2 and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-I reverse transcriptase and afford a method for prevention and treatment of HIV-I infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula (I) useful for the prevention and treatment of HIV-I infections and the treatment of AIDS and/or ARC.

La présente invention concerne des composés de formule (I), dans laquelle R1, R2, R3, X1, X2 et Ar, sont tels que définis dans le présent document ou des sels pharmaceutiquement acceptables de ceux-ci, qui inhibent la transcriptase inverse du VIH I et permettent un procédé de prévention et de traitement des infections dues au VIH I et de traitement du SIDA et/ou du syndrome pré-SIDA. La présente invention concerne également des compositions contenant des composés de formule (I) utiles pour la prévention et le traitement des infections dues au VIH I et pour le traitement du SIDA et/ou du syndrome pré-SIDA.

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