C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/64 (2006.01) A61K 31/44 (2006.01) A61P 31/12 (2006.01)
Patent
CA 2730517
Compounds having the formula (I) wherein R1, R2, R3, R4a' R4b' R4c', R5, R6, R9 and n are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
Cette invention concerne des composés de formule (I), R1, R2, R3, R4a' R4b' R4c', R5, R6, R9 et n étant tels que définis ici, lesdits composés étant des inhibiteurs de polymérase NS5b du virus de lhépatite C. Linvention concerne également des compositions et des méthodes de traitement dune infection au virus de lhépatite C et dinhibition de la réplication du VHC.
Brameld Kenneth Albert
Carter David Scott
Chin Elbert
de Vicente Fidalgo Javier
Li Jim
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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